Effects of the use of fortified raw maternal milk on very low birth weight infants.
نویسندگان
چکیده
OBJECTIVE To compare the weight and height gain and the frequency of clinical complications in preterm newborns weighing less than 1,500 g, exclusively fed human milk or fortified human milk until reaching 1,800 g. METHODS Prospective double-blind randomized controlled trial involving 40 preterm infants weighing < 1,500 g at birth and <or= 34 weeks of gestational age, admitted to a neonatal intensive care unit from August 2005 to April 2007. Preterm infants were randomized into two groups: control (human milk) and intervention (fortified human milk). Fortifiers were added to manually expressed human milk when feeding volume reached 100 mL/kg/day until newborns reached 1,800 g. Daily weight gain, weekly length and head circumference gain, nutritional variables and clinical complications were compared. RESULTS Human milk fortification resulted in better growth, with length gain of 1.09 and 0.87 cm/week (p = 0.003) and head circumference gain of 0.73 and 1.02 cm/week (p = 0.0001), respectively, for intervention and control groups. The weight gain was 24.4 and 21.1 g/day (p = 0.075). There were no significant clinical complications. CONCLUSIONS Human milk fortification resulted in better growth, significant increase in length and head circumference.
منابع مشابه
Growth in VLBW infants fed predominantly fortified maternal and donor human milk diets: a retrospective cohort study
BACKGROUND To determine the effect of human milk, maternal and donor, on in-hospital growth of very low birthweight (VLBW) infants. We performed a retrospective cohort study comparing in-hospital growth in VLBW infants by proportion of human milk diet, including subgroup analysis by maternal or donor milk type. Primary outcome was change in weight z-score from birth to hospital discharge. MET...
متن کاملEarly feeding of fortified breast milk and in-hospital-growth in very premature infants: a retrospective cohort analysis
BACKGROUND Fortified human milk may not meet all nutritional needs of very preterm infants. Early transition from complementary parenteral nutrition to full enteral feeds might further impair in-hospital growth. We aimed to investigate the impact of the cumulative intake of fortified human milk on early postnatal growth in a cohort of very low birth weight infants after early transition to full...
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متن کاملIncrease in Weight in Low Birth Weight and Very Low Birth Weight Infants Fed Fortified Breast Milk versus Formula Milk: A Retrospective Cohort Study
There has been a dramatic rise in preterm births in developed countries owing to changes in clinical practices and greater use of assisted reproductive techniques. However, few studies have examined the growth and outcomes of preterm infants according to the type of feeding (with fortified breast milk or formula). The purpose of this study was to examine the effect of breast milk feedings and f...
متن کاملO-27: Maternal Age and Low Birth Weight
Background: The weight of fetus at birth is widely acceptable parameter that can demonstrate the health of mother. Low birth weight (LBW) (birth weight less than 2500g) is significantly related to the neonatal survival and postnatal morbidity. Adolescence pregnancy is an important risk factor of LBW. The main objective of this study was therefore to determine the prevalence of LBW and relations...
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عنوان ژورنال:
- Jornal de pediatria
دوره 85 2 شماره
صفحات -
تاریخ انتشار 2009